Paracetamol (Acetaminophen) is Safe and Effective for Treatment of Postoperative Third Molar Extraction Pain

Article Title and Bibliographic Information

Paracetamol for pain relief after surgical removal of lower wisdom teeth.

Weil K, Hooper L, Afzal Z, Esposito M, Worthington HV, van Wijk A, et al.

Cochrane Database Syst Rev 2007;(3):CD004487. DOI: 10.1002/14651858.CD004487. pub2.

Reviewer

Robert Weyant, DMD, DrPH

Purpose/Question

This study's aim was to assess the benefits and harmful effects of Paracetamol (acetaminophen) for treatment of post-operative pain associated with extraction of lower third molars when compared to placebo.

Source of Funding

Internal funding from the University of Manchester (UK) and the University of Amsterdam (Netherlands). No external sources of funding supplied.

Type of Study/Design

Systematic review with meta-analysis.

Level of Evidence

Level 1: Good-quality, patient-oriented evidence.

Strength of Recommendation Grade

Grade B: Inconsistent or limited-quality patient-oriented evidence.