Journal of Evidence-Based Dental Practice
Volume 9, Issue 1 , Pages 21-22, March 2009

C-Reactive Protein Levels are Elevated in Patients with Periodontitis and Their CRP Levels May Go Down After Periodontal Therapy

Professor & Director, Graduate Program in Clinical Research, New York University College of Dentistry, 250 Park Ave South - 6th Floor, New York, NY 10003-1402

Article Title and Bibliographic Information

A systematic review and meta-analyses on C-reactive protein in relation to periodontitis.

Paraskevas S, Huizinga JD, Loos BG.

J Clin Periodontol 2008;35(4):277-90.

Level of Evidence

Level 1: Good-quality, patient-oriented evidence.

Strength of Recommendation Grade

Grade A: Consistent, good-quality patient-oriented evidence.

Purpose/Question

Are CRP levels significantly increased in periodontitis patients and what is the effect of periodontal therapy on their CRP levels?.

Source of Funding

Industry – Unrestricted grant from Philips Oral Healthcare EMEA.

Type of Study/Design

Systematic review and meta-analysis of observational and experimental studies.

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PII: S1532-3382(08)00222-4

doi:10.1016/j.jebdp.2008.12.010

Journal of Evidence-Based Dental Practice
Volume 9, Issue 1 , Pages 21-22, March 2009

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