Local Delivery of Tetracycline does not Improve Clinical Outcomes

Original Article

Meta-analysis of local tetracycline in treating chronic periodontitis.

Pavia M, Nobile CG, Angelillo IF.

J Periodontal 2003;74(6):916-32.

Level of Evidence

1a

Purpose

To assess the clinical effectiveness of local delivery of tetracycline alone or as an adjunct to conventional mechanical therapy in patients with chronic periodontitis by conducting a meta-analysis of published studies

Source of Funding

Government

Type of Study/Design

Systematic review