Premedication with Low-dose Dextromethorphan Does Not Reduce Pain Following Oral Surgery
Article Title and Bibliographic Information
Dextromethorphan Premedication Reduced Postoperative Analgesic Consumption in Patients After Oral Surgery
Aoki T, Yamaguchi H, Naito H, Shiiki K, Ota Y, Kaneko A.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;102(5):591-5
Level of Evidence
1b
Purpose/Question
To determine if premedication with the NMDA antagonist dextromethorphan reduces postoperative pain after oral surgery.
Source of Funding
Government: Japanese Ministry of Education
Type of Study/Design
Randomized Controlled Trial
University of Maryland, Baltimore, Baltimore College of Dental Surgery; Dental School, Department of Biomedical Sciences, 650 West Baltimore Street, Room 8209, Baltimore, MD 21201
ABSTRACT