Chlorhexidine (CHX) Gel Application has Moderate Effect on Salivary Mutans Streptococcal (MS) Levels, but Negligible Caries-Preventive Effect

Article Title and Bibliographic Information

Caries-Preventive Effect of Chlorhexidine Gel Applications Among High-Risk Children

Petti S, Hausen H.

Caries Res 2006;40(6):514-21

Level of Evidence

2b

Purpose/Question

What effect do CHX gels have on MS levels and on visible caries increments?

Source of Funding

None noted

Type of Study/Design

Prospective clinical trial with aspects of a cohort study (high versus low risk based on MS levels) and aspects of a nonrandomized clinical trial (test versus control in the high-risk group)