Bisphosphonates are associated with the development of exposed bone (osteonecrosis/osteopetrosis) in the oral cavity
Article Title and Bibliographic Information
Bisphosphonates-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention and treatment. Marx RE, Sawatary Y, Fortin M, Broumand V. J Oral Maxillofac Surg 2005;63:1567-75.
Level of Evidence
4
Purpose/Question
To determine type, dosage, and duration of bisphosphonate therapy; indication of use; clinical findings; comorbidities present; and the event that initiated the bone exposure.
Source of Funding
None disclosed
Type of Study/Design
Retrospective case series review
Professor – Oral Medicine NSU College of Dental Medicine 3200 S. University Drive Fort Lauderdale, FL 33328