The safety of amalgam compared with resin composite restorations in children older than 8 years showed no significant differences on neurobehavioral or nerve conduction studies during a 7-year follow-up
Article Title and Bibliographic Information
Neurobehavioral effects of dental amalgam in children: a randomized clinical trial. DeRouen TA, Martin MD, Leroux BG, Townes BD, Woods JS, Leitao J, et al. JAMA 2006;295(15):1784-92.
Level of Evidence
1b
Purpose/Question
The purpose of this study was to determine the effect of mercury vapor from dental amalgam on neurobehavioral variables and nerve conduction velocities in children.
Source of Funding
This study was funded by the National Institute of Dental and Craniofacial Research (NIDCR) of the National Institutes of Health.