Rofecoxib provides relief of pain following third molar extractions
Article Title and Bibliographic Information
Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain. Chang DJ, Bird SR, Bohidar NR, King T. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100(4):e74-80.
Level of Evidence
1b
Purpose/Question
The authors of this study planned to demonstrate the clinical advantage of single-dose rofecoxib 50 mg to single-dose APAP 600 mg/codeine 60 mg.
Source of Funding
Industry
Type of Study/Design
Randomized controlled trial
Professor, Pharmacology and Dental Public Health Chair, Department of Anesthesiology Director, Oral Health Science Institute 552 Salk Hall School of Dental Medicine University of Pittsburgh Pittsburgh, PA 15261