Genetics may have a significant contribution to dental caries while microbial acid production appears to be modulated by the environment

Article Title and Bibliographic Information

Dental caries and microbial acid production in twins.

Bretz WA, Corby PM, Hart TC, Costa S, Coelho MQ, Weyant RJ, et al. Caries Res 2005;39(3):168-72.

Level of Evidence

2b

Purpose/Question

To determine the genetic and environmental contributions to the occurrence of dental caries and microbial acid production in a cohort of monozygotic and dizygotic twins.

Source of Funding

Government – NIH/NIDCR

Type of Study/Design

Cohort study