Journal of Evidence-Based Dental Practice
Volume 5, Issue 3 , Pages 160-161, September 2005

DNA sequence variations in the genes MSX1 and TGFA may lead to developmentally missing teeth

Associate Professor, Pediatric Dentistry, School of Dentistry, University of Washington, Seattle, Washington

Original Article

Vieira AR, Meira R, Modesto A, Murray JC. MSX1, PAX9, and TGFA contribute to tooth agenesis in humans. J Dent Res 2004;83(9):723-7.

Level of Evidence

3b

Purpose

The purpose of this study was to determine the association between developmentally missing teeth (hypodontia) and sequence variations in the genes MSX1, PAX9, and TGFA in an ethnically diverse population.

Source of Funding

National Institutes of Health

Type of Study/Design

A case/parent trio study

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PII: S1532-3382(05)00103-X

doi:10.1016/j.jebdp.2005.06.015

Journal of Evidence-Based Dental Practice
Volume 5, Issue 3 , Pages 160-161, September 2005

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