Subantimicrobial dose doxycycline (SDD) improves probing parameters associated with periodontitis
Original Article
Preshaw PM, Hefti AF, Novak MJ, Michalowicz BS, Pihlstrom BL, Schoor R, et al. Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. J Periodontol 2004;75(8):1068-76.
Level of Evidence
1b
Purpose
The purpose of this randomized controlled clinical trial (RCT) was to compare the effect of scaling and root planning (SRP) plus subantimicrobial dose doxycycline (SDD) to adjunctive placebo in subjects with moderate to advanced chronic periodontitis.
Source of Funding
Industry
Type of Study/Design
Randomized controlled trial
Department of Periodontology, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina
ABSTRACT