Journal of Evidence-Based Dental Practice
Volume 5, Issue 3 , Pages 151-153, September 2005

Subantimicrobial dose doxycycline (SDD) improves probing parameters associated with periodontitis

  • David Paquette, DMD, MPH, DMSc (Associate Professor and Graduate Program Director)

Department of Periodontology, School of Dentistry, University of North Carolina, Chapel Hill, North Carolina

Original Article

Preshaw PM, Hefti AF, Novak MJ, Michalowicz BS, Pihlstrom BL, Schoor R, et al. Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. J Periodontol 2004;75(8):1068-76.

Level of Evidence

1b

Purpose

The purpose of this randomized controlled clinical trial (RCT) was to compare the effect of scaling and root planning (SRP) plus subantimicrobial dose doxycycline (SDD) to adjunctive placebo in subjects with moderate to advanced chronic periodontitis.

Source of Funding

Industry

Type of Study/Design

Randomized controlled trial

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PII: S1532-3382(05)00098-9

doi:10.1016/j.jebdp.2005.06.010

Journal of Evidence-Based Dental Practice
Volume 5, Issue 3 , Pages 151-153, September 2005

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