ALDH2 genotype is associated in the relation between alcohol intake and periodontitis
Original Article
Nishida N, Tanaka M, Hayashi N, Nagata H, Takeshita T, Nakayama K, et al. Association of ALDH(2) genotypes and alcohol consumption with periodontitis. J Dent Res 2004;83(2):161-5.
Level of Evidence
3b
Purpose
The ALD2 and ALDH2 genes are implicated in alcohol metabolism. Polymorphisms of these genes, common in Asian populations, slow alcohol metabolism. Because alcohol intake has been related to periodontitis, the authors wanted to test the periodontitis-alcohol relation within levels of polymorphisms of these genes.
Source of Funding
Japanese Society for the Promotion of Science and Japanese Dental Society
Type of Study/Design
Case-control study
Assistant Professor, McMaster University, Clinical Epidemiology and Biostatistics, Hamilton, Ontario, Canada
ABSTRACT