Valdecoxib (Bextra) is as effective as oxycodone/acetaminophen in reducing pain following oral surgery

References 

1. Cooper SA, Beaver WT. A model to evaluate mild analgesics in oral surgery outpatients. Clin Pharmacol Ther. 1976;20:241–250
   • MEDLINE
2. Jackson DL, Roszkowski MT, Moore PA. Management of acute postoperative. In:  Frost DE,  Hersh E,  Levin LM editor. Oral and maxillofacial surgery. Philadelphia: : W B Saunders; 2000;p. 114–140
3. Moore PA, Hersh EV. Celecoxib and rofecoxib: the role of COX-2 inhibitors in dental practice. J Am Dent Assoc. 2001;132:451–456
   • MEDLINE
4. Mahmstrom K, Daniels S, Kotey P, Seidenberg BC, Desjardin PJ. Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: a randomized, placebo- and active-comparator-controlled clinical trial. Clin Ther. 1999;21:1653–1663
   • Abstract
   • Full-Text PDF (831 KB)
   • CrossRef
5. Morrison BW, Christensen S, Weiying Y, Brown J, Amlani S, Seidenberg B. Analgesic efficacy of the cyclooxygenase-2-sepcific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial. Clin Therap. 1999;21:943–951
6. Ehlich EW, Dallob A, Lepeleire ID, Van Hecken A, Riendau D, Yaun W, et al. Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental model. Clin Pharmacol Ther. 1999;6:83–92
7. Henry D, Drew A, Beuzeville . Adverse drug reactions in the gastrointestinal system attributed to ibuprofen. In:  Rainsford KD,  Powanda MC editor. Safety and efficacy of non-prescription (OTC) analgesics and NSAIDs. Hingham (Mass): : Kluwer Academic Publishers; 1998;p. 19–45
8. Hersh EV, Moore PA, Ross GL. Over-the-counter analgesics and antipyretics: a critical assessment. Clin Ther. 2000;22:500–548
   • Abstract
   • Full-Text PDF (3713 KB)
   • CrossRef
9. Carson JL, Strom BL, Morse ML. The relative gastrointestinal toxicity of the nonsteroidal anti-inflammatory drugs. Arch Intern Med. 1987;147:1054–1059
   • MEDLINE
10. Silverstein FE, Faich G, Goldstein JL, Simon LS, Pincus T, Whelton A, et al.  Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. JAMA. 2000;284:1247–1255
    • MEDLINE
    • CrossRef
11. Bombardier C, Laine L, Reicin A, Shapiro D, Burgos-Vargas R, Davis B, et al.  Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. N Eng J Med. 2000;343:1520–1528
12. New safety information pertaining to BEXTRA (valdecoxib) [letter]. Skokie, Ill, and Groton: Conn: Pharmacia Corp and Pfizer Inc; 2002, Sept; #UD0029719